对于一些既往的热门赛道,比如GLP-1,最终能脱颖而出的仍将会是少数企业,决定因素是临床效果。尚未上市的产品必须要找到差异化优势:一是给药形式优化,不少人都会在意注射带来的疼痛和不便,所以口服剂型仍有空间;二是疗效,特别是减重效果、心血管获益等;三是给药频率,半衰期更长、给药频次更低的产品更有机会;四是长期安全性,降低不良反应,减少停药反弹等。
Claude Code worked for 20 or 30 minutes in total, and produced a Z80 emulator that was able to pass ZEXDOC and ZEXALL, in 1200 lines of very readable and well commented C code (1800 lines with comments and blank spaces). The agent was prompted zero times during the implementation, it acted absolutely alone. It never accessed the internet, and the process it used to implement the emulator was of continuous testing, interacting with the CP/M binaries implementing the ZEXDOC and ZEXALL, writing just the CP/M syscalls needed to produce the output on the screen. Multiple times it also used the Spectrum ROM and other binaries that were available, or binaries it created from scratch to see if the emulator was working correctly. In short: the implementation was performed in a very similar way to how a human programmer would do it, and not outputting a complete implementation from scratch “uncompressing” it from the weights. Instead, different classes of instructions were implemented incrementally, and there were bugs that were fixed via integration tests, debugging sessions, dumps, printf calls, and so forth.
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The vga666 was designed for small TFT displays, but because VGA is just analog RGB plus sync signals, it can drive any monitor that accepts the right timings. We needed two configuration files.
美國參謀長聯席會議主席丹·凱恩(Dan Caine)在週一的簡報會上表示,這些行動的明確目的,是「使伊朗陷入眩惑和混亂」。
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--memory "16G" --cpus "8" --shm-size="1G" \